Metallothioneins and Related Chelators () von Astrid Sigel

Metal Ions in Life Sciences links coordination chemistry and biochemistry in their widest sense and thus increases our understanding of the relationship between the chemistry of metals and life processes; in fact, it is an old wisdom that metals are indispensable for life. The series reflects the interdisciplinary nature of Biological Inorganic Chemistry and coordinates the efforts of scientists in numerous interconnecting research fields.

• Historical Development and Overview
• Regulation of Metallothionein Gene Expression
• Bacterial Metallothioneins
• Metallothioneins in Yeast and Fungi
• Metallothioneins in Plants
• Metallothioneins in Diptera
• Earthworm and Nematode Metallothioneins
• Metallothioneins in Aquatic Organisms: Fish, Crustaceans, Molluscs, and Echinoderms
• Metal Detoxification in Freshwater Animals. Roles of Metallothioneins
• Structure and Function of Vertebrate Metallothioneins
• Metallothionein-3, Zinc, and Copper in the Central Nervous System
• Metallothionein Toxicology: Metal Ion Trafficking and Cellular Protection
• Metallothionein in Inorganic Carcinogenesis
• Thioredoxins and Glutaredoxins. Functions and Metal Ion Interactions
• Metal Ion-Binding Poperties of Phytochelatins and Related Ligands
  

These sulfur-rich chelators, being important in metal ion homeostasis, find increasing attention. MILS-5, written by 30 internationally recognized experts, focuses on this hot topic. The reader is supported by about 20 tables, more than 80 illustrations and nearly 2000 references. This book is an essential resource for scientists working in a wide range of disciplines from environmental toxicology and inorganic biochemistry all the way through to physiology and medicine.

HelmutundAstrid Sigel, University of Basel, Switzerland.Roland K. O. Sigel, University of Zürich, Switzerland.